Will technology provide us the means to slow down and even reverse aging? If so, what are the consequences? Should we seek to avoid that outcome, or to accelerate towards it more quickly?
When you take a “cell’s eye” view of life, every cell alive today would consider itself to have been alive for some 4 billion years. From its perspective, it may have gone through many changes, halving and doubling the number of chromosomes periodically, etc, and it is still alive, though its genetic makeup may be very different from what it was 4 billion years ago.
Every time a cell divides, every cell considers the entity not it to be other. So lots of others, only one it.
Every cell alive has the same view – always.
Sure the particular collection of cells that is our bodies is much more recent (some 62 years in my case). But before all the cells in me were the zygote that became me, they were in my mother, and grandmother, and ………
So the default mode of cellular life must be indefinite – all this “senescence” must be a layer on top, and therefor able to be modified.
The latest work on the relationship of SETD8 to aging is very interesting.